PR Newswire
SAN DIEGO, Aug. 6, 2026
Total Revenue Increased 48% YOY to $481 million
Royalty Revenue Increased 50% YOY to $308 million
Raises 2026 Financial Guidance Ranges:
Total Revenue of $1.835 - $1.910 billion, YOY Growth of 31% - 37%
Royalty Revenue of $1.220 - $1.245 billion, YOY Growth of 41% - 43%
Adjusted EBITDA of $1.225 - $1.280 billion, YOY Growth of 86% - 95%1
Non-GAAP Diluted EPS of $8.65 - $9.00, YOY Growth of 108% - 117%1
Signed Five New ENHANZE® and Hypercon™ Collaboration Agreements YTD 2026, Exceeding Goal of Three for Full Year 2026
SAN DIEGO, Aug. 6, 2026 /PRNewswire/ -- Halozyme Therapeutics, Inc. (Nasdaq: HALO) ("Halozyme" or the "Company") today reported its financial and operating results for the second quarter ended June 30, 2026, and provided an update on its recent corporate activities.
"We delivered another quarter of strong performance, with multiple proof points demonstrating the attractive features of ENHANZE as a compounding platform engine: repeatability of success, scalability, diversification and durability of revenues," said Dr. Helen Torley, President and Chief Executive Officer. "Total revenue increased 48% year-over-year to $481 million, royalty revenue increased 50% to $308 million and adjusted EBITDA grew 46% to $329 million, reflecting the strength of our differentiated royalty business. Based on these record results, we are raising our full year 2026 financial guidance."
"Importantly, we are delivering on both our near-term and long-term growth objectives. The ENHANZE value proposition is attracting new partners and additional products from our current partners. We expanded our royalty revenue opportunity by signing five new ENHANZE and Hypercon collaborations through July, including agreements with Vertex, Oruka, GSK, Incyte and an undisclosed partner who is the first to license ENHANZE for a nucleic acid therapeutic. We have also demonstrated our commitment to returning significant capital to shareholders, repurchasing $333 million of shares in 2Q 2026, at an average price of $69.30. Overall, these results illustrate our continued ability to create multiple waves of revenue opportunities that will drive long-term shareholder value," concluded Dr. Torley.
Second Quarter Corporate Highlight:
Recent Partner Highlights:
Second Quarter Partner Highlights:
Second Quarter 2026 Financial Highlights:
Financial Outlook for 2026
The Company is raising its 2026 financial guidance ranges, which were last provided on May 11, 2026.
For the full year 2026, the Company expects:
Table 1. 2026 Financial Guidance
Previous Guidance Range | New Guidance Range | |||
Total Revenue | $1.710 to $1.810 billion | $1.835 to $1.910 billion | ||
Royalty Revenue | $1.130 to $1.170 billion | $1.220 to $1.245 billion | ||
Adjusted EBITDA1 | $1.125 to $1.205 billion | $1.225 to $1.280 billion | ||
Non-GAAP Diluted EPS1 | $7.75 to $8.25 | $8.65 to $9.00 |
1 EBITDA, Adjusted EBITDA and Non-GAAP Diluted EPS are Non-GAAP financial measures. See "Note Regarding Use of Non-GAAP Financial Measures" below for an explanation of these measures. Reconciliations between GAAP reported and Non-GAAP financial information for actual results are provided at the end of this earnings release. |
Webcast and Conference Call
Halozyme will host its Quarterly Update Conference Call for the second quarter ended June 30, 2026 today, Thursday, August 6, 2026, at 1:30 p.m. PT/4:30 p.m. ET. The conference call may be accessed live with pre-registration via link: https://events.q4inc.com/analyst/838122249?pwd=X5tkHKi. The call will also be webcast live through the "Investors" section of Halozyme's corporate website and a recording will be made available following the close of the call. To access the webcast and additional documents related to the call, please visit Halozyme.com.
About Halozyme
Halozyme is a biopharmaceutical company advancing disruptive solutions to improve patient experiences and outcomes for emerging and established therapies. As the innovators of ENHANZE® drug delivery technology with the proprietary enzyme rHuPH20, Halozyme's commercially-validated solution facilitates the subcutaneous delivery of injected drugs and fluids, reducing treatment burden and improving convenience. ENHANZE® has touched more than one million patient lives through ten commercialized products across over 100 global markets and is licensed to leading pharmaceutical and biotechnology companies including Roche, Takeda, Pfizer, Janssen, AbbVie, Eli Lilly, Bristol-Myers Squibb, argenx, ViiV Healthcare, Chugai Pharmaceutical, Acumen Pharmaceuticals, Merus N.V., Skye Bioscience, GSK and Incyte.
Halozyme expanded its drug delivery technology portfolio to develop partner products using Hypercon™ and Surf Bio's hyperconcentration technology. Hypercon™ is an innovative microparticle technology expected to set a new standard in hyperconcentration of drugs and biologics by reducing injection volume for the same dosage and enabling administration in at-home and healthcare-provider settings. The addition of Surf Bio's polymer-based hyperconcentration technology further broadens the range of biologics that can be delivered subcutaneously, meaningfully expanding the scope of opportunities across therapeutic modalities. Together, Hypercon™ and Surf Bio's technology complement ENHANZE® by enabling creation and delivery of highly concentrated biologics. The Hypercon™ technology has been licensed to leading biopharmaceutical partners, including Janssen, Eli Lilly, argenx, Vertex Pharmaceuticals, and Oruka Therapeutics.
Halozyme also develops, manufactures and commercializes drug-device combination products using advanced auto-injector technologies designed to improve convenience, reliability and tolerability, enhancing patient comfort and adherence. The Company has two proprietary commercial products, Hylenex® and XYOSTED®, partnered commercial products and ongoing development programs with Teva Pharmaceuticals and McDermott Laboratories Limited, an affiliate of Viatris Inc.
Halozyme is headquartered in San Diego, CA, with offices in Ewing, NJ; Minnetonka, MN; and Boston, MA. Minnetonka is also the site of its operations facility.
For more information, visit www.halozyme.com and connect with us on LinkedIn.
Note Regarding Use of Non-GAAP Financial Measures
In addition to disclosing financial measures prepared in accordance with U.S. generally accepted accounting principles ("GAAP"), this press release and the accompanying tables contain certain Non-GAAP financial measures. The Company reports earnings before interest, taxes, depreciation, and amortization ("EBITDA"), adjusted EBITDA, Non-GAAP diluted earnings per share, Non-GAAP diluted shares, and guidance with respect to those measures, in addition to, and not as a substitute for, or superior to, financial measures calculated in accordance with GAAP. The Company calculates Non-GAAP diluted earnings per share excluding share-based compensation expense, amortization of debt discounts, intangible asset amortization, one-time items, if any, such as changes in contingent liabilities, inventory adjustments, impairment charges, transaction costs for business combinations and share-based compensation acceleration expenses, intellectual property litigation costs, inducement expenses related to convertible notes, and certain adjustments to income tax expense. The Company calculates Non-GAAP diluted shares excluding the dilutive impact of convertible notes which is used in calculating Non-GAAP diluted earnings per share. The Company calculates EBITDA excluding interest, taxes, depreciation and amortization. The Company calculates adjusted EBITDA excluding one-time items, if any, such as changes in contingent liabilities, inventory adjustments, impairment charges, transaction costs for business combinations and share-based compensation acceleration expenses and intellectual property litigation costs. Reconciliations between GAAP and Non-GAAP financial measures are included at the end of this press release. The Company does not provide reconciliations for forward-looking adjusted measures to GAAP due to the inherent difficulty in forecasting and quantifying certain amounts that are necessary for such reconciliation, including adjustments that could be made for changes in share-based compensation expense and the effects of any discrete income tax items. For the same reasons, the Company is unable to address the probable significance of the unavailable information. The Company provides Non-GAAP financial measures that it believes will be achieved; however, it cannot accurately predict all of the components of the adjusted calculations and the GAAP measures may be materially different than the Non-GAAP measures.
The Company evaluates other items of income and expense on an individual basis for potential inclusion in the calculation of Non-GAAP financial measures and considers both the quantitative and qualitative aspects of the item, including (i) its size and nature, (ii) whether or not it relates to the Company's ongoing business operations and (iii) whether or not the Company expects it to occur as part of the Company's normal business on a regular basis. Non-GAAP financial measures do not have any standardized meaning and are therefore unlikely to be comparable to similarly titled measures presented by other companies. These Non-GAAP financial measures are not meant to be considered in isolation and should be read in conjunction with the Company's consolidated financial statements prepared in accordance with GAAP, and are not prepared under any comprehensive set of accounting rules or principles. In addition, from time to time in the future there may be other items that the Company may exclude for purposes of its Non-GAAP financial measures, and the Company may in the future cease to exclude items that it has historically excluded for purposes of its Non-GAAP financial measures.
The Company considers these Non-GAAP financial measures to be important because they provide useful measures of the operating performance of the Company, exclusive of factors that do not directly affect what the Company considers to be its core operating performance, as well as unusual events. The Non-GAAP measures also allow investors and analysts to make additional comparisons of the operating activities of the Company's core business over time and with respect to other companies, as well as assessing trends and future expectations. The Company uses Non-GAAP financial information in assessing what it believes is a meaningful and comparable set of financial performance measures to evaluate operating trends, as well as in establishing portions of our performance-based incentive compensation programs.
Safe Harbor Statement
In addition to historical information, the statements set forth in this press release include forward-looking statements including, without limitation, statements concerning the Company's financial performance (including the Company's expected financial outlook for 2026) and expectations for future growth, profitability, revenue durability, total revenue, royalty revenue, royalty revenue duration, EBITDA, Adjusted EBITDA, and non-GAAP diluted earnings-per-share, and shareholder value and potential future share repurchases. These forward-looking statements also include statements regarding the Company's potential receipt of upfront payments and payments associated with achievement of certain development, regulatory and sales-based milestones, and royalties on sales of commercialized products from recent collaboration agreements. Forward-looking statements regarding the Company's ENHANZE® drug delivery technology may include the possible benefits and attributes of ENHANZE®, its potential application to aid in the dispersion and absorption of other injected therapeutic drugs and facilitating more rapid delivery and administration of higher volumes of injectable medications through subcutaneous delivery including its potential application with antibody drug conjugates. Forward-looking statements regarding the Company's Hypercon™ and Surf Bio technologies include the possible benefits and attributes of these technologies, including the potential to reduce injection volume for the same dosage of drugs and biologics and possibly enabling administration in at‑home and healthcare‑provider settings and statements concerning certain other potential benefits of these technologies including facilitating administration of injectable medications through subcutaneous delivery by enabling creation and delivery of highly concentrated biologics and potentially lowering the treatment burden, easing treatment access and improving the treatment experience for patients. Forward-looking statements regarding the Company's business may include potential growth and receipt of royalty and milestone payments driven by our partners' development and commercialization efforts, potential new clinical trial study starts and advancement of partnered development programs, regulatory submissions and product launches, the size and growth prospects of our partners' drug franchises, potential new or expanded collaborations and collaborative targets, and potential approvals of new partnered or proprietary products, and the potential timing of these events. These forward-looking statements are typically, but not always, identified through use of the words "expect," "believe," "enable," "may," "will," "could," "intends," "estimate," "anticipate," "plan," "predict," "probable," "potential," "preliminary," "possible," "should," "continue," and other words of similar meaning and involve risk and uncertainties that could cause actual results to differ materially from those in the forward-looking statements. Actual results could differ materially from the expectations contained in these forward-looking statements as a result of several factors, including uncertainties concerning future matters such as unexpected results or delays in the Company's repurchases of the Company's shares under the share repurchase program, market conditions, changes in domestic and foreign business, changes in the competitive environment in which the Company operates, unexpected early expiration or termination of the patent terms for the Company's drug delivery technologies, unexpected levels of revenues, expenditures and costs, unexpected results or delays in the growth of the Company's business, or in the development, regulatory review or commercialization of the Company's partnered or proprietary products, regulatory approval requirements, unexpected adverse events or patient outcomes and competitive conditions. These and other factors that may result in differences are discussed in greater detail in the Company's most recent Annual Report on Form 10-K and Quarterly Report on Form 10-Q filed with the Securities and Exchange Commission, including under the headings "Risk Factors" and "Management's Discussion and Analysis of Financial Condition and Results of Operations". Except as required by law, the Company undertakes no duty to update forward-looking statements to reflect events after the date of this release.
Contacts:
Tram Bui
VP, Investor Relations and Corporate Communications
609-333-7668
tbui@halozyme.com
Sydney Charlton
Teneo
917-972-8407
sydney.charlton@teneo.com
Halozyme Therapeutics, Inc. Condensed Consolidated Statements of Operations (Unaudited) (In thousands, except per share amounts) | ||||||||
Three Months Ended | Six Months Ended | |||||||
June 30, | June 30, | |||||||
2026 | 2025 | 2026 | 2025 | |||||
Revenues | ||||||||
Royalties | $ 307,699 | $ 205,639 | $ 548,380 | $ 373,831 | ||||
Product sales, net | 129,626 | 81,510 | 260,050 | 159,551 | ||||
Revenues under collaborative agreements | 43,674 | 38,570 | 49,277 | 57,198 | ||||
Total revenues | 480,999 | 325,719 | 857,707 | 590,580 | ||||
Operating expenses | ||||||||
Cost of sales | 79,171 | 46,359 | 158,409 | 94,762 | ||||
Amortization of intangibles | 29,512 | 17,762 | 59,024 | 35,524 | ||||
Research and development | 27,664 | 17,543 | 53,224 | 32,342 | ||||
Selling, general and administrative | 56,998 | 41,614 | 114,879 | 83,976 | ||||
Total operating expenses | 193,345 | 123,278 | 385,536 | 246,604 | ||||
Operating income | 287,654 | 202,441 | 472,171 | 343,976 | ||||
Other income (expense) | ||||||||
Investment and other income, net | 2,836 | 6,891 | 4,154 | 13,709 | ||||
Interest expense | (5,588) | (4,394) | (11,096) | (8,919) | ||||
Income before income tax expense | 284,902 | 204,938 | 465,229 | 348,766 | ||||
Income tax expense | 54,989 | 39,778 | 85,267 | 65,511 | ||||
Net income | $ 229,913 | $ 165,160 | $ 379,962 | $ 283,255 | ||||
Earnings per share | ||||||||
Basic | $ 1.96 | $ 1.36 | $ 3.23 | $ 2.32 | ||||
Diluted | $ 1.90 | $ 1.33 | $ 3.11 | $ 2.26 | ||||
Weighted average common shares outstanding | ||||||||
Basic | 117,274 | 121,343 | 117,707 | 122,274 | ||||
Diluted | 121,215 | 124,158 | 122,092 | 125,452 | ||||
Halozyme Therapeutics, Inc. Condensed Consolidated Balance Sheets (Unaudited) (In thousands) | ||||
June 30, | December 31, | |||
ASSETS | ||||
Current assets | ||||
Cash and cash equivalents | $ 163,138 | $ 133,820 | ||
Marketable securities, available-for-sale | 67,865 | 9,000 | ||
Accounts receivable, net and contract assets | 455,827 | 441,273 | ||
Inventories | 137,135 | 176,475 | ||
Prepaid expenses and other current assets | 109,059 | 64,639 | ||
Total current assets | 933,024 | 825,207 | ||
Property and equipment, net | 84,271 | 82,137 | ||
Prepaid expenses and other assets | 55,090 | 53,551 | ||
Goodwill | 581,732 | 580,360 | ||
Intangible assets, net | 922,443 | 981,467 | ||
Restricted cash | 848 | 2,601 | ||
Total assets | $ 2,577,408 | $ 2,525,323 | ||
LIABILITIES AND STOCKHOLDERS' EQUITY | ||||
Current liabilities | ||||
Accounts payable | $ 23,608 | $ 20,899 | ||
Accrued expenses | 111,861 | 156,193 | ||
Current portion of long-term debt, net | 208,970 | — | ||
Total current liabilities | 344,439 | 177,092 | ||
Long-term debt, net | 1,937,684 | 2,142,630 | ||
Other long-term liabilities | 102,681 | 113,863 | ||
Deferred tax liabilities, net | 49,061 | 42,924 | ||
Total liabilities | 2,433,865 | 2,476,509 | ||
Stockholders' equity | ||||
Common stock | 114 | 118 | ||
Additional paid-in capital | — | 12,002 | ||
Accumulated other comprehensive loss | (7,830) | (18,092) | ||
Retained earnings | 151,259 | 54,786 | ||
Total stockholders' equity | 143,543 | 48,814 | ||
Total liabilities and stockholders' equity | $ 2,577,408 | $ 2,525,323 | ||
Halozyme Therapeutics, Inc. GAAP to Non-GAAP Reconciliations EBITDA (Unaudited) (In thousands) | ||||
Three Months Ended | ||||
June 30, | ||||
2026 | 2025 | |||
GAAP Net Income | $ 229,913 | $ 165,160 | ||
Adjustments | ||||
Investment and other income, net | (2,581) | (6,891) | ||
Interest expense | 5,588 | 4,394 | ||
Income tax expense | 54,989 | 39,778 | ||
Depreciation and amortization | 33,967 | 20,502 | ||
EBITDA | 321,876 | 222,943 | ||
Adjustments | ||||
Intellectual property litigation costs(1) | 6,936 | 2,561 | ||
Adjusted EBITDA | $ 328,812 | $ 225,504 | ||
(1) | Adjustment relates to litigation costs incurred by Halozyme in connection with Halozyme's patent infringement litigation against Merck Sharp & Dohme LLC ("Merck"). These charges are excluded because the Company does not believe they are reflective of the Company's ongoing business and operating results. |
Halozyme Therapeutics, Inc. GAAP to Non-GAAP Reconciliations Net Income and Diluted EPS (Unaudited) (In thousands, except per share amounts) | ||||
Three Months Ended | ||||
June 30, | ||||
2026 | 2025 | |||
GAAP Net Income | $ 229,913 | $ 165,160 | ||
Adjustments | ||||
Share-based compensation | 17,698 | 12,161 | ||
Amortization of debt discount | 2,253 | 1,852 | ||
Amortization of intangible assets | 29,512 | 17,762 | ||
Intellectual property litigation costs(1) | 6,936 | 2,561 | ||
Income tax effect of above adjustments(2) | (13,677) | (8,158) | ||
Non-GAAP Net Income | $ 272,635 | $ 191,338 | ||
GAAP Diluted EPS | $ 1.90 | $ 1.33 | ||
Adjustments | ||||
Share-based compensation | 0.15 | 0.10 | ||
Amortization of debt discount | 0.02 | 0.01 | ||
Amortization of intangible assets | 0.25 | 0.14 | ||
Intellectual property litigation costs(1) | 0.06 | 0.02 | ||
Income tax effect of above adjustments(2) | (0.11) | (0.07) | ||
Non-GAAP Diluted EPS | $ 2.28 | $ 1.54 | ||
GAAP Diluted Shares | 121,215 | 124,158 | ||
Adjustments | ||||
Adjustment for dilutive impact of 2028 Convertible Senior Notes(3) | (1,497) | (199) | ||
Non-GAAP Diluted Shares | 119,718 | 123,959 | ||
Dollar amounts, as presented, are rounded. Consequently, totals may not add up. | |
(1) | Adjustment relates to litigation costs incurred by Halozyme in connection with Halozyme's patent infringement litigation against Merck. These charges are excluded because the Company does not believe they are reflective of the Company's ongoing business and operating results. |
(2) | Adjustments relate to taxes for the reconciling items, as well as excess benefits or tax deficiencies from share-based compensation, and the quarterly impact of other discrete items. |
(3) | Adjustment made for the dilutive effect of our Convertible Senior Notes due 2028 when the effect is not the same on a GAAP and Non-GAAP basis for the reporting period. |

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SOURCE Halozyme Therapeutics, Inc.